The most recent Carolina Panthers vs Arizona Cardinals matchup was played on September 14, 2025, at State Farm Stadium in Glendale, Arizona. The Cardinals defeated the Panthers 27–22 after building a 27–3 lead before Carolina mounted a fourth-quarter comeback. Arizona improved to 2–0, while Carolina fell to 0–2.
The matchup featured strong passing production from Bryce Young, efficient quarterback play from Kyler Murray, a 100-yard receiving performance by Tetairoa McMillan, and a decisive defensive play from Arizona linebacker Zaven Collins, who returned a fumble for a touchdown.
Key Statistics
Carolina Panthers vs Arizona Cardinals — September 14, 2025
| Statistic | Carolina Panthers | Arizona Cardinals |
|---|---|---|
| Final Score | 22 | 27 |
| First Downs | 26 | 16 |
| Total Yards | 352 | 293 |
| Passing Yards | 303 | 211 |
| Rushing Yards | 49 | 82 |
| Turnovers | 2 | 1 |
| Passing TDs | 3 | 1 |
| Rushing TDs | 0 | 1 |
| Sacks Allowed | 3 | 1 |
| Result | Loss | Win |
| Record After Game | 0–2 | 2–0 |
Despite producing 59 more total yards and 10 more first downs, Carolina lost because Arizona created key turnovers and converted its early opportunities into points.
Passing Statistics
| Player | Team | Cmp | Att | Pass Yds | TD | INT | Sacks | Rating |
|---|---|---|---|---|---|---|---|---|
| Bryce Young | CAR | 35 | 55 | 328 | 3 | 1 | 3 | 90.6 |
| Kyler Murray | ARI | 17 | 25 | 220 | 1 | 1 | 1 | 92.1 |
Bryce Young completed 35 of 55 passes for 328 yards, with three touchdown passes and one interception. Kyler Murray completed 17 of 25 attempts for 220 yards, one touchdown and one interception.
Rushing Statistics
| Player | Team | Carries | Rushing Yards | TD | Long |
|---|---|---|---|---|---|
| James Conner | ARI | 11 | 34 | 1 | 8 |
| Trey Benson | ARI | 3 | 14 | 0 | 11 |
| Kyler Murray | ARI | 7 | 32 | 0 | 30 |
| Chuba Hubbard | CAR | 10 | 38 | 0 | 14 |
| Rico Dowdle | CAR | 6 | 9 | 0 | 5 |
| Bryce Young | CAR | 2 | 2 | 0 | 3 |
Arizona’s rushing attack was led by James Conner’s 34 yards and touchdown, while Kyler Murray added 32 rushing yards. Carolina’s leading rusher was Chuba Hubbard with 38 yards.
Receiving Statistics
| Player | Team | Targets | Receptions | Receiving Yards | TD | Long |
|---|---|---|---|---|---|---|
| Tetairoa McMillan | CAR | 10 | 6 | 100 | 0 | 40 |
| Ja’Tavion Sanders | CAR | 9 | 7 | 54 | 0 | 12 |
| Hunter Renfrow | CAR | 9 | 7 | 48 | 2 | 15 |
| Chuba Hubbard | CAR | 6 | 5 | 39 | 1 | 16 |
| Trey McBride | ARI | 7 | 6 | 78 | 0 | 31 |
| Elijah Higgins | ARI | 3 | 2 | 45 | 0 | 27 |
| Marvin Harrison Jr. | ARI | 5 | 2 | 27 | 0 | 15 |
| Trey Benson | ARI | 6 | 4 | 30 | 0 | 12 |
| Michael Wilson | ARI | 2 | 1 | 11 | 1 | 11 |
Tetairoa McMillan was Carolina’s leading receiver with 100 yards on six catches, while Arizona tight end Trey McBride led the Cardinals with 78 receiving yards. Hunter Renfrow caught two touchdown passes for Carolina.
Career Overview
The Carolina Panthers and Arizona Cardinals are NFC opponents that have developed a significant head-to-head history since Carolina entered the NFL in 1995.
According to the Panthers’ official series history, Carolina entered the 2025 meeting with a strong advantage in the matchup. The Panthers’ official historical page lists Carolina at 15–6 all-time against Arizona, including a 2–1 playoff record. The 2025 regular-season meeting subsequently gave Arizona another victory.
Pro Football Reference’s matchup database records 22 meetings between the franchises, including postseason games, with Carolina leading 15–7 overall, 13–6 in the regular season, and 2–1 in the playoffs after the 2025 game.
The matchup has included several significant postseason games, most notably Carolina’s 49–15 victory over Arizona in the 2015 NFC Championship Game.
Career Statistics
Because “Carolina Panthers vs Arizona Cardinals match player stats” describes a team matchup rather than one individual player’s career, the most relevant career-level statistics are the franchises’ head-to-head totals.
All-Time Head-to-Head Team Statistics
| Category | Carolina Panthers | Arizona Cardinals |
|---|---|---|
| Regular-Season Games | 19 | 19 |
| Regular-Season Wins | 13 | 6 |
| Regular-Season Losses | 6 | 13 |
| Regular-Season Points | 465 | 370 |
| Playoff Games | 3 | 3 |
| Playoff Wins | 2 | 1 |
| Playoff Losses | 1 | 2 |
| Total Games | 22 | 22 |
| Total Points | 554 | 434 |
The regular-season totals through the 2025 matchup show Carolina with a 13–6 advantage, while the Panthers also lead the playoff series 2–1.
Head-to-Head Passing Totals
| Team | Completions | Attempts | Completion % | Passing Yards | TD | INT |
|---|---|---|---|---|---|---|
| Carolina | 385 | 619 | 62.2% | 4,059 | 29 | 15 |
| Arizona | 412 | 662 | 62.2% | 3,975 | 25 | 29 |
Carolina has accumulated more passing yards in the series despite Arizona attempting more passes. Both teams have a 62.2% completion rate in the regular-season head-to-head data.
Head-to-Head Rushing Totals
| Team | Attempts | Rushing Yards | Yards/Attempt | TD |
|---|---|---|---|---|
| Carolina | 563 | 2,542 | 4.5 | 20 |
| Arizona | 457 | 1,842 | 4.0 | 12 |
Carolina has produced 700 more rushing yards and eight more rushing touchdowns across the regular-season series.
Season-by-Season Stats
Recent Carolina Panthers vs Arizona Cardinals Results
| Season | Venue | Carolina | Arizona | Result |
|---|---|---|---|---|
| 2019 | Arizona | 38 | 20 | CAR win |
| 2020 | Carolina | 31 | 21 | CAR win |
| 2021 | Arizona | 34 | 10 | CAR win |
| 2022 | Carolina | 16 | 26 | ARI win |
| 2024 | Carolina | 36 | 30 | CAR win, OT |
| 2025 | Arizona | 22 | 27 | ARI win |
Carolina won four of the six most recent meetings entering the current season, including the 2024 overtime game. Arizona’s 2025 victory made the recent series more competitive.
2024 Matchup
On December 22, 2024, Carolina defeated Arizona 36–30 in overtime at Bank of America Stadium. Chuba Hubbard delivered the winning 21-yard rushing touchdown in overtime.
| Player | Team | Key Statistics |
|---|---|---|
| Bryce Young | CAR | 17/26, 158 pass yds, 2 pass TD, 68 rush yds, 1 rush TD |
| Chuba Hubbard | CAR | 25 rush, 152 yds, 2 TD |
| Adam Thielen | CAR | 5 rec, 43 yds, 1 TD |
| David Moore | CAR | 2 rec, 39 yds, 1 TD |
| Kyler Murray | ARI | 20/32, 202 pass yds, 1 pass TD, 1 INT |
| James Conner | ARI | 15 rush, 117 yds, 1 TD |
| Michael Carter | ARI | 5 rush, 18 yds; 5 rec, 30 yds |
2025 Matchup
The September 14, 2025 game reversed the previous year’s result, with Arizona winning 27–22.
| Player | Team | Key Statistics |
|---|---|---|
| Bryce Young | CAR | 35/55, 328 pass yds, 3 TD, 1 INT |
| Tetairoa McMillan | CAR | 6 rec, 100 yds |
| Hunter Renfrow | CAR | 7 rec, 48 yds, 2 TD |
| Chuba Hubbard | CAR | 10 rush, 38 yds; 5 rec, 39 yds, 1 TD |
| Kyler Murray | ARI | 17/25, 220 pass yds, 1 TD, 1 INT; 7 rush, 32 yds |
| Trey McBride | ARI | 6 rec, 78 yds |
| James Conner | ARI | 11 rush, 34 yds, 1 TD |
| Michael Wilson | ARI | 1 rec, 11 yds, 1 TD |
Records
Carolina Panthers vs Arizona Cardinals Series Records
| Record | Statistic |
|---|---|
| Carolina regular-season wins | 13 |
| Arizona regular-season wins | 6 |
| Carolina playoff wins | 2 |
| Arizona playoff wins | 1 |
| Carolina total series wins | 15 |
| Arizona total series wins | 7 |
| Carolina regular-season points | 465 |
| Arizona regular-season points | 370 |
| Highest Carolina score | 49 |
| Highest Arizona score | 33 |
| Most recent meeting | Arizona 27–22, 2025 |
Notable Single-Game Milestones
- Carolina scored 49 points against Arizona in the 2015 NFC Championship Game.
- Carolina won the 2015 NFC Championship 49–15.
- The 2024 meeting ended 36–30 in overtime.
- Chuba Hubbard rushed for 152 yards and two touchdowns in the 2024 meeting.
- Bryce Young threw for 328 yards and three touchdowns in the 2025 meeting.
- Tetairoa McMillan recorded his first 100-yard receiving performance in the matchup with six receptions for 100 yards.
Awards and Honors
The matchup itself does not have an official annual individual award. Relevant player honors and career achievements connected with the teams include:
| Player | Team | Relevant Recognition |
|---|---|---|
| Bryce Young | Carolina | No game-specific award verified for the 2025 matchup |
| Kyler Murray | Arizona | 2019 NFL Offensive Rookie of the Year |
| James Conner | Arizona | 2021 Pro Bowl |
| Chuba Hubbard | Carolina | 2024 Pro Bowl |
| Calais Campbell | Arizona | Six-time Pro Bowl selection and former All-Pro |
No official source reviewed for the 2025 Panthers-Cardinals game identifies an individual game MVP award. The Arizona game report specifically highlighted Calais Campbell’s closing sack as the play that sealed the 27–22 victory.
Performance Trends
Bryce Young
Young’s passing volume was the defining statistical feature of the 2025 matchup. He attempted 55 passes, completing 35 for 328 yards. His three touchdown passes helped Carolina erase much of a 24-point deficit, but the Panthers could not complete the comeback.
His 2025 performance was considerably more productive statistically than his 2024 game against Arizona:
| Season | Comp/Att | Pass Yards | Pass TD | INT | Rush Yards |
|---|---|---|---|---|---|
| 2024 vs ARI | 17/26 | 158 | 2 | 0 | 68 |
| 2025 vs ARI | 35/55 | 328 | 3 | 1 | 2 |
Kyler Murray
Murray produced a more efficient passing line than Young in the 2025 game, completing 68.0% of his attempts compared with Young’s 63.6%. Murray also contributed 32 rushing yards and a rushing touchdown in the previous 2024 meeting.
Chuba Hubbard
Hubbard’s two most recent games against Arizona show a major change in workload and production:
- 2024: 25 carries, 152 rushing yards, 2 rushing TDs.
- 2025: 10 carries, 38 rushing yards, plus five receptions for 39 yards and a receiving touchdown.
Arizona’s Defensive Impact
Arizona’s defense produced the decisive early turnover. Josh Sweat strip-sacked Bryce Young, and Zaven Collins returned the fumble for a touchdown. Calais Campbell later recorded the game-clinching sack.
Historical Context
The Panthers have historically controlled this matchup. Before the 2025 season, Carolina had won 13 of 18 regular-season meetings against Arizona. The Panthers also won two of three playoff meetings.
The 2015 NFC Championship Game represents the largest postseason meeting between the franchises. Carolina won 49–15, advancing to Super Bowl 50.
The statistical history also shows Carolina’s advantage on the ground. Through the regular-season series, the Panthers have produced 2,542 rushing yards at 4.5 yards per attempt, compared with Arizona’s 1,842 yards at 4.0 yards per attempt.
Passing efficiency has been much closer. Both teams have a 62.2% completion rate in the regular-season head-to-head statistics, although Carolina has thrown for 4,059 yards compared with Arizona’s 3,975.
Head-to-Head Statistics
All-Time Series
| Category | Carolina Panthers | Arizona Cardinals |
|---|---|---|
| Overall Games | 22 | 22 |
| Overall Wins | 15 | 7 |
| Regular Season | 13–6 | 6–13 |
| Playoffs | 2–1 | 1–2 |
| Regular-Season Points | 465 | 370 |
| All-Time Points Including Playoffs | 554 | 434 |
Last Six Meetings
| Date | Winner | Score |
|---|---|---|
| Sep. 22, 2019 | Carolina | CAR 38–20 |
| Oct. 4, 2020 | Carolina | CAR 31–21 |
| Nov. 14, 2021 | Carolina | CAR 34–10 |
| Oct. 2, 2022 | Arizona | ARI 26–16 |
| Dec. 22, 2024 | Carolina | CAR 36–30 OT |
| Sep. 14, 2025 | Arizona | ARI 27–22 |
2025 Head-to-Head Player Comparison
| Category | Bryce Young | Kyler Murray |
|---|---|---|
| Completions | 35 | 17 |
| Attempts | 55 | 25 |
| Completion % | 63.6% | 68.0% |
| Passing Yards | 328 | 220 |
| Passing TD | 3 | 1 |
| Interceptions | 1 | 1 |
| Rushing Attempts | 2 | 7 |
| Rushing Yards | 2 | 32 |
| Total Offensive Yards | 330 | 252 |
Recent Form
The September 14, 2025 matchup was Arizona’s second game of the season and Carolina’s second game of the season. Arizona entered the game 1–0 and moved to 2–0 after defeating Carolina. The Panthers dropped to 0–2.
Carolina later finished the 2025 regular season with a winning record and reached the playoffs, where it lost 34–31 to the Los Angeles Rams in the Wild Card Round.
For the 2025 Panthers-Cardinals matchup specifically, the statistical pattern was clear:
- Carolina dominated passing volume.
- Arizona produced more rushing yards.
- Carolina gained more total yards.
- Arizona created the more damaging turnover.
- Carolina scored three fourth-quarter touchdowns but could not overcome its early deficit.
- Arizona’s defense made the final decisive play with Campbell’s sack of Young.
Statistical Highlights
- Final score: Arizona 27, Carolina 22.
- Bryce Young: 35/55 passing, 328 yards, 3 TD, 1 INT.
- Kyler Murray: 17/25 passing, 220 yards, 1 TD, 1 INT.
- Tetairoa McMillan: 6 receptions, 100 yards.
- Hunter Renfrow: 7 receptions, 48 yards, 2 touchdowns.
- Trey McBride: 6 receptions, 78 yards.
- James Conner: 11 carries, 34 yards, 1 rushing touchdown.
- Carolina total offense: 352 yards.
- Arizona total offense: 293 yards.
- Carolina passing offense: 303 yards.
- Arizona passing offense: 211 yards.
- Carolina rushing offense: 49 yards.
- Arizona rushing offense: 82 yards.
- 2024 Chuba Hubbard performance: 152 rushing yards and two touchdowns.
- All-time regular-season series: Carolina leads 13–6.
- All-time playoff series: Carolina leads 2–1.
- Largest Carolina score against Arizona: 49 points in the 2015 NFC Championship Game.
Frequently Asked Questions
What was the final score of the Carolina Panthers vs Arizona Cardinals game?
The Arizona Cardinals defeated the Carolina Panthers 27–22 on September 14, 2025, at State Farm Stadium.
Who was the Panthers’ leading passer?
Bryce Young led Carolina with 35 completions on 55 attempts for 328 yards, three touchdowns and one interception.
Who was the Cardinals’ leading passer?
Kyler Murray completed 17 of 25 passes for 220 yards, one touchdown and one interception.
Who led Carolina in receiving?
Rookie wide receiver Tetairoa McMillan led Carolina with six receptions for 100 yards.
Who led Arizona in receiving?
Tight end Trey McBride recorded six receptions for 78 yards.
Who led the Panthers in rushing?
Chuba Hubbard led Carolina with 10 carries for 38 yards.
Who led the Cardinals in rushing?
James Conner had 11 carries for 34 yards and one touchdown, while Kyler Murray added 32 rushing yards.
Did the Panthers win the 2024 matchup?
Yes. Carolina defeated Arizona 36–30 in overtime on December 22, 2024. Chuba Hubbard scored the winning 21-yard rushing touchdown in overtime.
What is the Panthers’ all-time record against the Cardinals?
Through the 2025 meeting, Carolina has a 15–7 overall record against Arizona, including a 13–6 regular-season record and a 2–1 playoff record.
What was the biggest Panthers win over the Cardinals?
Carolina’s largest listed victory came in the 2015 NFC Championship Game, when the Panthers defeated Arizona 49–15.
Who scored Arizona’s defensive touchdown in the 2025 game?
Zaven Collins returned a fumble for a touchdown after Josh Sweat strip-sacked Bryce Young. The defensive touchdown helped Arizona establish its early lead.
Sources and References
The statistics in this article were cross-checked against official team information and established football statistical databases:
- Carolina Panthers official website — series history and 2025 schedule.
- Arizona Cardinals official website — 2025 game report and defensive highlights.
- Pro Football Reference — complete 2025 and 2024 box scores, player statistics, game results and historical head-to-head records.
- Stathead / Sports Reference — historical head-to-head passing, rushing and team statistics.
- Pro Football Archives — independent verification of the 2024 Panthers-Cardinals box score.

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